Neural cell protective compounds isolated from Phoenix hanceana var. formosana.

@article{Lin2009NeuralCP,
  title={Neural cell protective compounds isolated from Phoenix hanceana var. formosana.},
  author={Y T Lin and T Y Chen and Hsiang-Wen Tseng and Michael Lee and Shui-Tein Chen},
  journal={Phytochemistry},
  year={2009},
  volume={70 9},
  pages={1173-81}
}
A platform for screening drugs for their ability to protect neuronal cells against cytotoxicity was developed. Nerve growth factor (NGF) differentiates PC12 cells into nerves, and these differentiated PC12 cells enter apoptosis when challenged with 6-hydroxydopamine (6-OHDA). A screening spectrophotometer was used to assay cytotoxicity in these cells; pretreatment with test samples allowed identification of compounds that protected against this neuronal cytotoxicity. The 95% ethanol extract of… CONTINUE READING
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