Neural cell adhesion molecule distribution in soft tissue tumors.

  title={Neural cell adhesion molecule distribution in soft tissue tumors.},
  author={Markku Miettinen and W Cupo},
  journal={Human pathology},
  volume={24 1},
The distribution of the neural cell adhesion molecule (N-CAM; CD56) was studied immunohistochemically in acetone-fixed frozen sections of 83 soft tissue tumors and selected normal mesenchymal tissue using Leu-19 monoclonal antibody and avidin-biotin peroxidase immunostaining. Positive N-CAM immunostaining was found in gastrointestinal and uterine cells but not in vascular smooth muscle cells. Normal skeletal muscle was negative, but atrophic muscle fibers within tumors were positive. Strong and… CONTINUE READING


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