Neural cell adhesion molecule and prognosis of surgically resected lung cancer.

@article{Pujol1993NeuralCA,
  title={Neural cell adhesion molecule and prognosis of surgically resected lung cancer.},
  author={Jean-Louis Pujol and Jo{\"e}lle Simony and Pascal Demoly and Roberta Charpentier and Jennifer Laurent and J. P. Daur{\`e}s and Matthias Lehmann and Val{\'e}rie Guyot and P A Godard and François B. Michel},
  journal={The American review of respiratory disease},
  year={1993},
  volume={148 4 Pt 1},
  pages={1071-5}
}
The prognostic significance of the expression of neural cell adhesion molecule (NCAM), a neuroendocrine antigen in lung cancer, was analyzed by an indirect immunoperoxidase method in 97 surgically treated patients. Reactivity of MOC-1 and S-L 11.14, both cluster-1 monoclonal antibodies directed against NCAM, was positive in all nine small-cell lung cancers and in 16 of 88 (18%) non-small-cell lung cancers. For the latter group, this expression demonstrated a phenotypic heterogeneity that was… CONTINUE READING

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