Neural cadherin is expressed in human gametes and participates in sperm-oocyte interaction events.

@article{MarnBriggiler2010NeuralCI,
  title={Neural cadherin is expressed in human gametes and participates in sperm-oocyte interaction events.},
  author={Clara Mar{\'i}n-Briggiler and Lara Lapyckyj and M F Gonz{\'a}lez Echeverr{\'i}a and Vanesa Yanina Rawe and Cristian Roberto Alvarez Sedo and M{\'o}nica Hebe Vazquez-Levin},
  journal={International journal of andrology},
  year={2010},
  volume={33 1},
  pages={e228-39}
}
Neural cadherin (N-cadherin) is a transmembrane glycoprotein involved in calcium-dependent cell-cell adhesion and signalling events. The previous evidence shows N-cadherin expression in the human gonads and gametes; however, N-cadherin subcellular localization in human spermatozoa and oocytes, and its involvement in fertilization remain to be characterized. In this study, expression of N-cadherin in human spermatozoa and testis was confirmed by RT-PCR and protein forms were identified using… CONTINUE READING