Neural background of glucocorticoid dysfunction-induced abnormal aggression in rats: involvement of fear- and stress-related structures.

@article{Halasz2002NeuralBO,
  title={Neural background of glucocorticoid dysfunction-induced abnormal aggression in rats: involvement of fear- and stress-related structures.},
  author={Jozsef Halasz and Zsolt Liposits and Menno R. Kruk and J{\'o}zsef Haller},
  journal={The European journal of neuroscience},
  year={2002},
  volume={15 3},
  pages={561-9}
}
Glucocorticoid hypofunction is associated with persistent aggression in some psychologically disordered human subjects and, as reported recently, induces abnormal forms of aggression in rats. Here we report on the effects of glucocorticoid hypofunction on aggression-induced neural activation. Rats were adrenalectomized, and implanted with low-release glucocorticoid pellets. After one week recovery, they were challenged by an unfamiliar intruder in their home-cage. Neural activation was studied… CONTINUE READING

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