Neural and behavioral plasticity associated with the transition from controlled to escalated cocaine use.


BACKGROUND Rats given extended access to cocaine develop several symptoms of addiction, including a gradual escalation of drug intake, whereas rats given limited access do not. We asked here whether extended access to cocaine also produces drug-induced sensitization, a form of neurobehavioral plasticity implicated in addiction. METHODS Rats were given… (More)


5 Figures and Tables

Slides referencing similar topics