Neural Substrates for the Effects of Rehabilitative Training on Motor Recovery After Ischemic Infarct

@article{Nudo1996NeuralSF,
  title={Neural Substrates for the Effects of Rehabilitative Training on Motor Recovery After Ischemic Infarct},
  author={Randolph J. Nudo and Breanne M. Wise and Francisco Ulises Pastor Sifuentes and Garrett W. Milliken},
  journal={Science},
  year={1996},
  volume={272},
  pages={1791 - 1794}
}
Substantial functional reorganization takes place in the motor cortex of adult primates after a focal ischemic infarct, as might occur in stroke. A subtotal lesion confined to a small portion of the representation of one hand was previously shown to result in a further loss of hand territory in the adjacent, undamaged cortex of adult squirrel monkeys. In the present study, retraining of skilled hand use after similar infarcts resulted in prevention of the loss of hand territory adjacent to the… Expand
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