Neural Modulation by Blocks and Infusions

@article{Varrassi2006NeuralMB,
  title={Neural Modulation by Blocks and Infusions},
  author={Giustino Varrassi and Antonella Paladini and Franco Marinangeli and Gabor B. Racz},
  journal={Pain Practice},
  year={2006},
  volume={6}
}
Abstract:  Neural blockade is widely used in clinical practice to alleviate acute or chronic pain, including neuropathic pain. However, to date there is little controlled evidence to confirm the efficacy of nerve blocks in neuropathic pain. The most common indication for nerve blocks, especially sympathetic blockade, is complex regional pain syndrome, in which success rates of up to 38% have been achieved, depending on the type of the block used. Greater efficacy has been achieved by combining… 
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TLDR
The results suggest that peripheral nerve block with 80 mg depo-methylprednisolone plus 0.5% lidocaine provides effective management in the treatment of neuropathic pain due to peripheral nerve damage.
F250 MANAGEMENT OF NEUROPATHIC PAIN WITH METHYLPREDNISOLONE AT THE SITE OF NERVE INJURY
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A graded approach, from least to most invasive interventions has the potential to improve outcomes in many patients with common refractory NP conditions, and preliminary promising data warrant further research on new indications.
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TLDR
The dysfunction of bidirectional neural pathways and viscerovisceral cross-interactions within the central nervous system has been proposed as a possible central hypersensitization disorder responsible for the extraintestinal manifestations of IBS.
Successful Treatment of Chronic Donor Site Pain
TLDR
A 45-year-old male with a six year history of severe pain over the right iliac crest following an otherwise successful lumbar laminectomy and fusion underwent two sets of superior cluneal nerve blocks, with sustained relief of more than 80% at seven months follow up.
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