Neural Differentiation of Embryonic Stem Cells In Vitro: A Road Map to Neurogenesis in the Embryo

@inproceedings{Abranches2009NeuralDO,
  title={Neural Differentiation of Embryonic Stem Cells In Vitro: A Road Map to Neurogenesis in the Embryo},
  author={Elsa Abranches and Margarida Silva and Laurent Pradier and Herbert Schulz and Oliver Hummel and Domingos Henrique and Evguenia P. Bekman},
  booktitle={PloS one},
  year={2009}
}
BACKGROUND The in vitro generation of neurons from embryonic stem (ES) cells is a promising approach to produce cells suitable for neural tissue repair and cell-based replacement therapies of the nervous system. Available methods to promote ES cell differentiation towards neural lineages attempt to replicate, in different ways, the multistep process of embryonic neural development. However, to achieve this aim in an efficient and reproducible way, a better knowledge of the cellular and… CONTINUE READING
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