Neural Crest and the Origin of Vertebrates: A New Head

  title={Neural Crest and the Origin of Vertebrates: A New Head},
  author={Carl Gans and R. Glenn Northcutt},
  pages={268 - 273}
Most of the morphological and functional differences between vertebrates and other chordates occur in the head and are derived embryologically from muscularized hypomere, neural crest, and epidermal (neurogenic) placodes. In the head, the neural crest functions as mesoderm and forms connective, skeletal, and muscular tissue. Both the neural crest and the epidermal placodes form special sense organs and other neural structures. These structures may be homologous to portions of the epidermal… 

The neural crest in vertebrate evolution.

Evolutionary and Developmental Associations of Neural Crest and Placodes in the Vertebrate Head: Insights From Jawless Vertebrates

The developmental mechanisms and genetics of neural crest and placodes in both jawed and jawless vertebrates are summarized and comparisons with jawed vertebrates can provide insights into the causes and consequences of this event in early vertebrate evolution are discussed.

The origins of the neural crest. Part II: an evolutionary perspective

Origins and plasticity of neural crest cells and their roles in jaw and craniofacial evolution.

Recent findings concerning the inductive origins of neural crest cells are discussed, as well as new insights into the mechanisms patterning this cell population and the subsequent influence this has had on craniofacial evolution are discussed.

Progenitors of the protochordate ocellus as an evolutionary origin of the neural crest

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Evolution of neural crest and placodes: amphioxus as a model for the ancestral vertebrate?

Comparisons of developmental gene expression data suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons.

Development and evolution of the neural crest: an overview.

The neural crest, a multifaceted structure of the vertebrates.

The in vitro analysis of the developmental capacities of single NC cells (NCC) showed that they present several analogies with the hematopoietic cells whose differentiation involves the activity of stem cells endowed with different arrays of developmental potentialities.



A radioautographic study of the migration and fate of cranial neural crest cells in the chick embryo

The migration and fate of cranial neural fold cells of the chick embryo (White Leghorn strain) were followed radioautographically after replacing crestcontaining fold segments with comparable

Mesenchymal derivatives of the neural crest: analysis of chimaeric quail and chick embryos.

It appears from this study that the differentiating capabilities are similar in mesenchymal and mesectodermal cells with the exception of blood vessel endothelia which in the authors' experiments are always of host origin in mesectoderm-derived tissues.

Participation of neural crest-derived cells in the genesis of the skull in birds

It appears that the cephalic neural crest is particularly important in the formation of the facial part of the skull, while the vault and dorsal part are mesodermal and cartilages and bones found in the intermediary region are of mixed origin.

Neural crest and placodal contributions in the development of the glossopharyngeal‐vagal complex in the chick

It is concluded that the neurons of the trunk ganglia are purely placodal in origin and are composed of a population of cells of the large‐cell type.

An experimental study on neural crest migration in Barbus conchonius (Cyprinidae, Teleostei), with special reference to the origin of the enteroendocrine cells.

Evidence is presented for a neural crest origin of spinal ganglion cells and pigment cells, and indication for such an origin is obtained for sympathetic and enteric ganglION cells and for cells that are probably homologues to adrenomedullary and paraganglions in the future kidney area.