Neural Cell Apoptosis Induced by Microwave Exposure Through Mitochondria-dependent Caspase-3 Pathway

  title={Neural Cell Apoptosis Induced by Microwave Exposure Through Mitochondria-dependent Caspase-3 Pathway},
  author={Hongyan Zuo and Tao Lin and Dewen Wang and Ruiyun Peng and Shuiming Wang and Yabing Gao and Xinping Xu and Yang Li and Shaoxia Wang and Lu Zhao and Lifeng Wang and Hongmei Zhou},
  booktitle={International journal of medical sciences},
To determine whether microwave (MW) radiation induces neural cell apoptosis, differentiated PC12 cells and Wistar rats were exposed to 2.856 GHz for 5 min and 15 min, respectively, at an average power density of 30  mW/cm². JC-1 and TUNEL staining detected significant apoptotic events, such as the loss of mitochondria membrane potential and DNA fragmentation, respectively. Transmission electron microscopy and Hoechst staining were used to observe chromatin ultrastructure and apoptotic body… CONTINUE READING
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