Neural-Cardiac Coupling in Threat-Evoked Anxiety

  title={Neural-Cardiac Coupling in Threat-Evoked Anxiety},
  author={Kim M. Dalton and Ned H. Kalin and Thomas M. Grist and Richard J. Davidson},
  journal={Journal of Cognitive Neuroscience},
Anxiety is a debilitating symptom of many psychiatric disorders including generalized anxiety disorder, mood disorders, schizophrenia, and autism. Anxiety involves changes in both central and peripheral biology, yet extant functional imaging studies have focused exclusively on the brain. Here we show, using functional brain and cardiac imaging in sequential brain and cardiac magnetic resonance imaging (MRI) sessions in response to cues that predict either threat (a possible shock) or safety (no… CONTINUE READING