Neural Adaptation Leads to Cognitive Ethanol Dependence

@article{Robinson2012NeuralAL,
  title={Neural Adaptation Leads to Cognitive Ethanol Dependence},
  author={Brooks G. Robinson and Sukant Khurana and Anna Kuperman and Nigel S. Atkinson},
  journal={Current Biology},
  year={2012},
  volume={22},
  pages={2338-2341}
}
Physiological alcohol dependence is a key adaptation to chronic ethanol consumption that underlies withdrawal symptoms, is thought to directly contribute to alcohol addiction behaviors, and is associated with cognitive problems such as deficits in learning and memory. Based on the idea that an ethanol-adapted (dependent) animal will perform better in a learning assay than an animal experiencing ethanol withdrawal will, we have used a learning paradigm to detect physiological ethanol dependence… CONTINUE READING
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