Network simulation reveals significant contribution of network motifs to the age-dependency of yeast protein-protein interaction networks.

@article{Liang2014NetworkSR,
  title={Network simulation reveals significant contribution of network motifs to the age-dependency of yeast protein-protein interaction networks.},
  author={Cheng Liang and Jiawei Luo and Dan Song},
  journal={Molecular bioSystems},
  year={2014},
  volume={10 9},
  pages={2277-88}
}
Advances in proteomic technologies combined with sophisticated computing and modeling methods have generated an unprecedented amount of high-throughput data for system-scale analysis. As a result, the study of protein-protein interaction (PPI) networks has garnered much attention in recent years. One of the most fundamental problems in studying PPI networks is to understand how their architecture originated and evolved to their current state. By investigating how proteins of different ages are… CONTINUE READING