Network pharmacology-based prediction of the multi-target capabilities of the compounds in Taohong Siwu decoction, and their application in osteoarthritis

@inproceedings{Zheng2013NetworkPP,
  title={Network pharmacology-based prediction of the multi-target capabilities of the compounds in Taohong Siwu decoction, and their application in osteoarthritis},
  author={Chun-song Zheng and Xiaojie Xu and Hong-zhi Ye and Guang-Wen Wu and Xi-Hai Li and Hui-Feng Xu and Xian-xiang Liu},
  booktitle={Experimental and therapeutic medicine},
  year={2013}
}
Taohong Siwu decoction (THSWD), a formulation prescribed in traditional Chinese medicine (TCM), has been widely used in the treatment of osteoarthritis (OA). TCM has the potential to prevent diseases, such as OA, in an integrative and holistic manner. However, the system-level characterization of the drug-target interactions of THSWD has not been elucidated. In the present study, we constructed a novel modeling system, by integrating chemical space, virtual screening and network pharmacology… CONTINUE READING

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Taohong Siwu decoction ( THSWD ) , a formulation prescribed in traditional Chinese medicine ( TCM ) , has been widely used in the treatment of osteoarthritis ( OA ) .
Taohong Siwu decoction ( THSWD ) , a formulation prescribed in traditional Chinese medicine ( TCM ) , has been widely used in the treatment of osteoarthritis ( OA ) .
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