Network biomarkers reveal dysfunctional gene regulations during disease progression.

  title={Network biomarkers reveal dysfunctional gene regulations during disease progression.},
  author={Tao Zeng and Shao-Yan Sun and Yong Wang and Hailong Zhu and Luonan Chen},
  journal={The FEBS journal},
  volume={280 22},
Extensive studies have been conducted on gene biomarkers by exploring the increasingly accumulated gene expression and sequence data generated from high-throughput technology. Here, we briefly report on the state-of-the-art research and application of biomarkers from single genes (i.e. gene biomarkers) to gene sets (i.e. group or set biomarkers), gene networks (i.e. network biomarkers) and dynamical gene networks (i.e. dynamical network biomarkers). In particular, differential and dynamical… CONTINUE READING
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