Network-based gene expression analysis of intracranial aneurysm tissue reveals role of antigen presenting cells

@article{Krischek2008NetworkbasedGE,
  title={Network-based gene expression analysis of intracranial aneurysm tissue reveals role of antigen presenting cells},
  author={Boris Krischek and Hidetoshi Kasuya and Atsushi Tajima and Hiroyuki Akagawa and Takuya Sasaki and Taku Yoneyama and Hiroshi Ujiie and Osami Kubo and Michael Bonin and Kohki Takakura and Tomoko Hori and Itsuro Inoue},
  journal={Neuroscience},
  year={2008},
  volume={154},
  pages={1398-1407}
}
Little is known about the pathology and pathogenesis of the rupture of intracranial aneurysms. For a better understanding of the molecular processes involved in intracranial aneurysm (IA) formation we performed a gene expression analysis comparing ruptured and unruptured aneurysm tissue to a control artery. Tissue samples of six ruptured and four unruptured aneurysms, and four cerebral arteries serving as controls, were profiled using oligonucleotide microarrays. Gene ontology classification of… CONTINUE READING
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