Network analysis reveals crosstalk between autophagy genes and disease genes

@inproceedings{Wang2017NetworkAR,
  title={Network analysis reveals crosstalk between autophagy genes and disease genes},
  author={Ji-ye Wang and Wei-Xuan Yao and Yun Hui Wang and Yi-lei Fan and Jian-Bing Wu},
  booktitle={Scientific reports},
  year={2017}
}
Autophagy is a protective and life-sustaining process in which cytoplasmic components are packaged into double-membrane vesicles and targeted to lysosomes for degradation. Accumulating evidence supports that autophagy is associated with several pathological conditions. However, research on the functional cross-links between autophagy and disease genes remains in its early stages. In this study, we constructed a disease-autophagy network (DAN) by integrating known disease genes, known autophagy… CONTINUE READING
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