Network Features and Dynamical Landscape of Naive and Primed Pluripotency.

Abstract

Although the broad and unique differentiation potential of pluripotent stem cells relies on a complex transcriptional network centered around Oct4, Sox2, and Nanog, two well-distinct pluripotent states, called "naive" and "primed", have been described in vitro and markedly differ in their developmental potential, their expression profiles, their signaling… (More)
DOI: 10.1016/j.bpj.2017.10.033

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