Netrins guide Drosophila commissural axons at short range

  title={Netrins guide Drosophila commissural axons at short range},
  author={Marko Brankatschk and Barry J. Dickson},
  journal={Nature Neuroscience},
Netrins are secreted axon guidance molecules required for commissure formation in a wide range of animal species, including Caenorhabditis elegans, Drosophila melanogaster and mice. They are generally thought to function as chemoattractants, acting at a distance to direct commissural axon growth toward the midline of the central nervous system. We show here, however, that D. melanogaster commissural axons still orient normally and reach the midline even in the complete absence of netrins… CONTINUE READING
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