Netrin 1 mediates spinal cord oligodendrocyte precursor dispersal.

@article{Tsai2003Netrin1M,
  title={Netrin 1 mediates spinal cord oligodendrocyte precursor dispersal.},
  author={Hui-Hsin Tsai and Marc Tessier-Lavigne and Robert H. Miller},
  journal={Development},
  year={2003},
  volume={130 10},
  pages={2095-105}
}
In spinal cord, oligodendrocyte precursors that give rise to myelin-forming cells originate in a restricted domain of the ventral ventricular zone. During development, these cells migrate widely throughout the spinal cord. Netrin 1 is expressed at the ventral ventricular zone during oligodendrocyte precursors emigration, and, in vitro, netrin 1 acts as chemorepellent and antagonizes platelet-derived growth factor (PDGF) chemoattraction. Oligodendrocyte precursors express the netrin receptors… CONTINUE READING
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