Netrin-1 is a survival factor during commissural neuron navigation.

@article{Furne2008Netrin1IA,
  title={Netrin-1 is a survival factor during commissural neuron navigation.},
  author={C{\'e}line Furne and Nicolas Rama and V{\'e}ronique Corset and Alain Ch{\'e}dotal and Patrick Mehlen},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 38},
  pages={14465-70}
}
DCC (Deleted in Colorectal Cancer) is a putative tumor suppressor whose expression is lost in numerous cancers and whose tumor suppressor activity appears to be dependent on its ability to trigger apoptosis when disengaged by its ligand netrin-1. In this sense, netrin-1 is a survival factor that controls tumorigenesis. However, netrin-1 is also the prototypical axon guidance cue and has been shown to orient many neurons or axons, especially commissural axons, during spinal cord development… CONTINUE READING

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