Netrin-1 guides inflammatory cell migration to control mucosal immune responses during intestinal inflammation

Abstract

The intestinal epithelium is a dynamic barrier playing an active role in intestinal homeostasis and inflammation. Intestinal barrier function is dysregulated during inflammatory bowel disease (IBD), with epithelial cells playing a significant part in generating an inflammatory milieu through the release of signals that attract leukocytes to the intestinal… (More)
DOI: 10.4161/tisb.24957

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