Neto auxiliary proteins control both the trafficking and biophysical properties of the kainate receptor GluK1

@inproceedings{Sheng2015NetoAP,
  title={Neto auxiliary proteins control both the trafficking and biophysical properties of the kainate receptor GluK1},
  author={Nengyin Sheng and Yun Stone Shi and Richa Madan Lomash and Katherine W. Roche and Roger A Nicoll},
  booktitle={eLife},
  year={2015}
}
Kainate receptors (KARs) are a subfamily of glutamate receptors mediating excitatory synaptic transmission and Neto proteins are recently identified auxiliary subunits for KARs. However, the roles of Neto proteins in the synaptic trafficking of KAR GluK1 are poorly understood. Here, using the hippocampal CA1 pyramidal neuron as a null background system we find that surface expression of GluK1 receptor itself is very limited and is not targeted to excitatory synapses. Both Neto1 and Neto2… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 38 references

hippocampus. Science 271:1294–1297

  • J Palacios-Filardo, MI Aller, J. Lerma
  • Cerebral Cortex
  • 2014
Highly Influential
4 Excerpts

phosphorylation of stargazin-like TARPs. Neuron 45:269–277

  • MS Wyeth, KA Pelkey, RS Petralia, MW Salter, RR McInnes, CJ. McBain
  • 2014
Highly Influential
5 Excerpts

Distinct functions of kainate

  • C Straub, DL Hunt, +4 authors S. Tomita
  • 2011
Highly Influential
4 Excerpts

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