NetB and necrotic enteritis: the hole movable story.

  title={NetB and necrotic enteritis: the hole movable story.},
  author={Julian I Rood and Anthony L. Keyburn and Robert J Moore},
  journal={Avian pathology : journal of the W.V.P.A},
  volume={45 3},
Clostridium perfringens is the primary causative agent of avian necrotic enteritis. Our understanding of the pathogenesis of this economically important disease has been enhanced by the discovery of C. perfringens NetB toxin, which belongs to the α-haemolysin family of β-pore-forming toxins. In a chicken disease model, the analysis of an isogenic set of strains comprising the wild type, a netB mutant, and its complemented derivative, fulfilled molecular Koch's postulates and revealed that NetB… CONTINUE READING
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