Net clinical benefit of antithrombotic therapy in patients with atrial fibrillation and chronic kidney disease: a nationwide observational cohort study.

@article{Bonde2014NetCB,
  title={Net clinical benefit of antithrombotic therapy in patients with atrial fibrillation and chronic kidney disease: a nationwide observational cohort study.},
  author={Anders Nissen Bonde and Gregory Y. H. Lip and A L Kamper and Peter Riis Hansen and Morten Lamberts and Kristine Hommel and Morten Hansen and Gunnar Hilmar Gislason and C Torp-Pedersen and Jonas Bjerring Olesen},
  journal={Journal of the American College of Cardiology},
  year={2014},
  volume={64 23},
  pages={2471-82}
}
BACKGROUND The balance between stroke reduction and increased bleeding associated with antithrombotic therapy among patients with atrial fibrillation (AF) and chronic kidney disease (CKD) is controversial. OBJECTIVES This study assessed the risk associated with CKD in individual CHA₂DS₂-VASc (Congestive heart failure; Hypertension; Age ≥75 years; Diabetes mellitus; previous Stroke, transient ischemic attack, or thromboembolism; Vascular disease; Age 65 to 74 years; Sex category) strata and… CONTINUE READING