Net adenine nucleotide transport in rat liver mitochondria is affected by both the matrix and the external ATP/ADP ratios.

@article{Austin1983NetAN,
  title={Net adenine nucleotide transport in rat liver mitochondria is affected by both the matrix and the external ATP/ADP ratios.},
  author={Jill Austin and June R. Aprille},
  journal={Archives of biochemistry and biophysics},
  year={1983},
  volume={222 1},
  pages={321-5}
}
The adenine nucleotide pool size of rat liver mitochondria may be regulated by a transport mechanism which allows net movement of ATP or ADP across the inner mitochondrial membrane (J. R. Aprille and J. Austin (1981) Arch. Biochem. Biophys. 212, 689-699). Since transport can occur in either direction, and ATP is the preferred substrate, variations in the matrix or external ATP/ADP ratio were examined for an effect on the direction and rate of net adenine nucleotide flux. Fastest rates of net… CONTINUE READING
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