Nestin small interfering RNA (siRNA) reduces cell growth in cultured astrocytoma cells.

@article{Wei2008NestinSI,
  title={Nestin small interfering RNA (siRNA) reduces cell growth in cultured astrocytoma cells.},
  author={Li-Chun Wei and Mei Shi and Rong Cao and L-W Antony Chen and Y Chan},
  journal={Brain research},
  year={2008},
  volume={1196},
  pages={103-12}
}
Nestin is an embryonic intermediate filament that transiently expressed in the neural stem/progenitor cells in the developing central nervous system (CNS). Growing evidence has shown that abundant expression of nestin also occurs in both pathological glial-derived tumor cells and reactive astrocytes in various CNS injuries, implying that nestin may play a crucial role in cell growth or proliferation of astrocyte-derived tumor cells. In the present study, we have investigated the possible role… CONTINUE READING