Nestin-positive microvessel density is an independent prognostic factor in breast cancer.

@article{Nowak2017NestinpositiveMD,
  title={Nestin-positive microvessel density is an independent prognostic factor in breast cancer.},
  author={Aleksandra Nowak and Jedrzej Grzegrzolka and Maria Paprocka and Aleksandra Piotrowska and Janusz Ryś and Rafal A Matkowski and Piotr Dzięgiel},
  journal={International journal of oncology},
  year={2017},
  volume={51 2},
  pages={668-676}
}
The process of angiogenesis based on new vessel formation within the tumour area plays a significant role in the progression of breast cancer. Nestin is an intermediate filament protein and participates in the cytoskeleton organization. Nestin expression in the endothelium of blood vessels is mainly limited to newly forming vessels, thus being a more… CONTINUE READING