Nestin-positive mesenchymal stem cells favour the astroglial lineage in neural progenitors and stem cells by releasing active BMP4

  title={Nestin-positive mesenchymal stem cells favour the astroglial lineage in neural progenitors and stem cells by releasing active BMP4},
  author={Sabine Wislet-Gendebien and F. Bruy{\`e}re and G. Hans and P. Leprince and G. Moonen and B. Rogister},
  journal={BMC Neuroscience},
  pages={33 - 33}
  • Sabine Wislet-Gendebien, F. Bruyère, +3 authors B. Rogister
  • Published 2004
  • Biology, Medicine
  • BMC Neuroscience
  • BackgroundSpontaneous repair is limited after CNS injury or degeneration because neurogenesis and axonal regrowth rarely occur in the adult brain. As a result, cell transplantation has raised much interest as potential treatment for patients with CNS lesions. Several types of cells have been considered as candidates for such cell transplantation and replacement therapies. Foetal brain tissue has already been shown to have significant effects in patients with Parkinson's disease. Clinical use of… CONTINUE READING
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