Nestin-positive mesenchymal stem cells favour the astroglial lineage in neural progenitors and stem cells by releasing active BMP4
@article{WisletGendebien2004NestinpositiveMS, title={Nestin-positive mesenchymal stem cells favour the astroglial lineage in neural progenitors and stem cells by releasing active BMP4}, author={Sabine Wislet-Gendebien and F. Bruy{\`e}re and G. Hans and P. Leprince and G. Moonen and B. Rogister}, journal={BMC Neuroscience}, year={2004}, volume={5}, pages={33 - 33} }
BackgroundSpontaneous repair is limited after CNS injury or degeneration because neurogenesis and axonal regrowth rarely occur in the adult brain. As a result, cell transplantation has raised much interest as potential treatment for patients with CNS lesions. Several types of cells have been considered as candidates for such cell transplantation and replacement therapies. Foetal brain tissue has already been shown to have significant effects in patients with Parkinson's disease. Clinical use of… CONTINUE READING
Tables and Topics from this paper
Tables
88 Citations
Role of mesenchymal stem cells in neurogenesis and nervous system repair
- Biology, Medicine
- Neurochemistry International
- 2011
- 119
Mesenchymal stem cells expressing neural antigens instruct a neurogenic cell fate on neural stem cells
- Biology, Medicine
- Experimental Neurology
- 2009
- 57
Coaxing bone marrow stromal mesenchymal stem cells towards neuronal differentiation: progress and uncertainties
- Biology, Medicine
- Cellular and Molecular Life Sciences CMLS
- 2006
- 104
Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke
- Medicine
- Journal of Clinical Neuroscience
- 2009
- 141
Mesenchymal stem cells enhance the engraftment and myelinating ability of allogeneic oligodendrocyte progenitors in dysmyelinated mice.
- Biology, Medicine
- Stem cells and development
- 2011
- 58
- PDF
Neuroectodermally converted human mesenchymal stromal cells provide cytoprotective effects on neural stem cells and inhibit their glial differentiation.
- Biology, Medicine
- Cytotherapy
- 2010
- 15
Adult stem cell therapies for neurological disorders: Benefits beyond neuronal replacement?
- Biology, Medicine
- Journal of neuroscience research
- 2009
- 36
Homing of allogeneic nestin-positive hair follicle-associated pluripotent stem cells after maternal transplantation in experimental model of cortical dysplasia.
- Biology, Medicine
- Biochemistry and cell biology = Biochimie et biologie cellulaire
- 2015
- 5
Cord blood mesenchymal stem cells: Potential use in neurological disorders.
- Biology, Medicine
- Stem cells and development
- 2006
- 54
References
SHOWING 1-10 OF 71 REFERENCES
Regulation of neural markers nestin and GFAP expression by cultivated bone marrow stromal cells
- Biology, Medicine
- Journal of Cell Science
- 2003
- 171
- PDF
Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats--similarities to astrocyte grafts.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1998
- 923
- PDF
Differentiation of transplanted bone marrow cells in the adult mouse brain.
- Biology, Medicine
- Transplantation
- 2001
- 95
Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells
- Biology, Medicine
- The Journal of experimental medicine
- 1999
- 392
- PDF
Bone marrow stromal cells enhance differentiation of cocultured neurosphere cells and promote regeneration of injured spinal cord
- Medicine
- Journal of neuroscience research
- 2003
- 226
- PDF
Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1999
- 1,635
- PDF
Transgenic overexpression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment.
- Biology, Medicine
- Developmental biology
- 2003
- 257
- PDF