Nestin expression in reactive astrocytes following focal cerebral ischemia in rats.

@article{Duggal1997NestinEI,
  title={Nestin expression in reactive astrocytes following focal cerebral ischemia in rats.},
  author={Neil Duggal and Rainald Schmidt-Kastner and Antoine M. Hakim},
  journal={Brain research},
  year={1997},
  volume={768 1-2},
  pages={1-9}
}
During central nervous system (CNS) development, intermediate filaments are subjected to a sequential remodelling process. Nestin is a distinct intermediate filament which is transiently expressed in proliferating neuroepithelial stem cells during the neurulation stage of development. Nestin re-expression in the adult rat was studied following transient (2 h) middle cerebral artery occlusion. Seven days after the ischemic insult, nestin reactive astrocytes were found in the border zone… CONTINUE READING

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