Nestin expression during mouse eye and lens development

  title={Nestin expression during mouse eye and lens development},
  author={Jing Yang and Wei Bian and Xiang Gao and Leping Chen and Naihe Jing},
  journal={Mechanisms of Development},
Nestin is an intermediate filament protein, which is expressed predominantly in the developing central nervous system and skeletal muscles. In situ hybridization revealed that mouse nestin mRNA is in the optic stalk at 9.0 days post coitus (dpc) and in the lens vesicle at 10.0 dpc. From 14.5 dpc onward, nestin transcripts appear in lens fibers and neuroretina. Immunohistochemistry showed that nestin protein appears in the optic stalk at 9.5 dpc and in the posterior lens epithelium at 10.5 dpc… CONTINUE READING