Nested uncertainties in biochemical models.

  title={Nested uncertainties in biochemical models.},
  author={J{\"o}rg Schaber and Wolfram Liebermeister and Edda Klipp},
  journal={IET systems biology},
  volume={3 1},
Dynamic modelling of biochemical reaction networks has to cope with the inherent uncertainty about biological processes, concerning not only data and parameters but also kinetics and structure. These different types of uncertainty are nested within each other: uncertain network structures contain uncertain reaction kinetics, which in turn are governed by uncertain parameters. Here, the authors review some issues arising from such uncertainties and sketch methods, solutions and future directions… CONTINUE READING
Highly Cited
This paper has 52 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.
23 Citations
40 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 23 extracted citations

52 Citations

Citations per Year
Semantic Scholar estimates that this publication has 52 citations based on the available data.

See our FAQ for additional information.


Publications referenced by this paper.
Showing 1-10 of 40 references

A Universal Rate Equation for Systems Biology. in ESCEC

  • J. M. Rohwer, A. J. Hanekom, J.-H.S. Hofmeyr
  • 2006
1 Excerpt

Similar Papers

Loading similar papers…