Nesiritide, renal function, and associated outcomes during hospitalization for acute decompensated heart failure: results from the Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure (ASCEND-HF).

@article{Deursen2014NesiritideRF,
  title={Nesiritide, renal function, and associated outcomes during hospitalization for acute decompensated heart failure: results from the Acute Study of Clinical Effectiveness of Nesiritide and Decompensated Heart Failure (ASCEND-HF).},
  author={Vincent M van Deursen and Adrian F. Hernandez and Amanda S Stebbins and Vic Hasselblad and Justin A Ezekowitz and Robert M. Califf and Stephen S Gottlieb and Christopher M. O'Connor and Randall C. Starling and Weihong Tang and John J V McMurray and Kenneth Dickstein and Adriaan Alexander Voors},
  journal={Circulation},
  year={2014},
  volume={130 12},
  pages={958-65}
}
BACKGROUND Contradictory results have been reported on the effects of nesiritide on renal function in patients with acute decompensated heart failure. We studied the effects of nesiritide on renal function during hospitalization for acute decompensated heart failure and associated outcomes. METHODS AND RESULTS A total of 7141 patients were randomized to receive either nesiritide or placebo and creatinine was recorded in 5702 patients at baseline, after infusion, discharge, peak/nadir levels… CONTINUE READING
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