Nesfatin-1: a novel inhibitory regulator of food intake and body weight.

@article{Stengel2011Nesfatin1AN,
  title={Nesfatin-1: a novel inhibitory regulator of food intake and body weight.},
  author={Andreas Stengel and Maria G{\"o}bel and Yvette F. Tach{\'e}},
  journal={Obesity reviews : an official journal of the International Association for the Study of Obesity},
  year={2011},
  volume={12 4},
  pages={261-71}
}
The protein nucleobindin 2 (NUCB2) or NEFA (DNA binding/EF-hand/acidic amino acid rich region) was identified over a decade ago and implicated in intracellular processes. New developments came with the report that post-translational processing of hypothalamic NUCB2 may result in nesfatin-1, nesfatin-2 and nesfatin-3 and convergent studies showing that nesfatin-1 and full length NUCB2 injected in the brain potently inhibit the dark phase food intake in rodents including leptin receptor deficient… CONTINUE READING

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