Nesfatin-1: a novel inhibitory regulator of food intake and body weight.

  title={Nesfatin-1: a novel inhibitory regulator of food intake and body weight.},
  author={Andreas Stengel and Maria G{\"o}bel and Yvette F. Tach{\'e}},
  journal={Obesity reviews : an official journal of the International Association for the Study of Obesity},
  volume={12 4},
The protein nucleobindin 2 (NUCB2) or NEFA (DNA binding/EF-hand/acidic amino acid rich region) was identified over a decade ago and implicated in intracellular processes. New developments came with the report that post-translational processing of hypothalamic NUCB2 may result in nesfatin-1, nesfatin-2 and nesfatin-3 and convergent studies showing that nesfatin-1 and full length NUCB2 injected in the brain potently inhibit the dark phase food intake in rodents including leptin receptor deficient… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 25 extracted citations

Nesfatin-1, a unique regulatory neuropeptide of the brain.

Neuropeptides • 2012
View 15 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…