Nervous system physiology regulated by membrane estrogen receptors.

  title={Nervous system physiology regulated by membrane estrogen receptors.},
  author={Paul G Mermelstein and Paul E Micevych},
  journal={Reviews in the neurosciences},
  volume={19 6},
Our understanding of estrogen signaling in the nervous system has undergone a significant shift in recent years. For over three decades, the idea that all estradiol actions were explained by direct regulation of transcription held sway. Within the past decade, the idea that in addition to classical effects, membrane-initiated actions of estradiol are important has gained traction. While several novel putative membrane estrogen receptors (ERs) have been described, a large fraction of measured… CONTINUE READING
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