Nerve terminal withdrawal from rat neuromuscular junctions induced by neuregulin and Schwann cells.

@article{Trachtenberg1997NerveTW,
  title={Nerve terminal withdrawal from rat neuromuscular junctions induced by neuregulin and Schwann cells.},
  author={Joshua T. Trachtenberg and Wesley J. Thompson},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1997},
  volume={17 16},
  pages={
          6243-55
        }
}
Schwann cells (SCs) that cap neuromuscular junctions (nmjs) play roles in guiding nerve terminal growth in paralyzed and partially denervated muscles; however, the role of these cells in the day-to-day maintenance of this synapse is obscure. Neuregulins, alternatively spliced ligands for several erbB receptor tyrosine kinases, are thought to play important roles in cell-cell communication at the nmj, affecting synapse-specific gene expression in muscle fibers and the survival of terminal SCs… CONTINUE READING

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