Nerve ischaemia in diabetic rats: time-course of development, effect of insulin treatment plus comparison of streptozotocin and BB models

@article{Stevens1994NerveII,
  title={Nerve ischaemia in diabetic rats: time-course of development, effect of insulin treatment plus comparison of streptozotocin and BB models},
  author={E. J. Stevens E. J. Stevens and Anne L Carrington and Prof. D. R. Tomlinson},
  journal={Diabetologia},
  year={1994},
  volume={37},
  pages={43-48}
}
This study sought to determine the timecourse of development of reduced nerve laser Doppler flux in experimental diabetes and the effect on this anomaly of insulin treatment. In addition, we aimed to compare nerve laser Doppler flux in streptozotocin-and genetically-diabetic BB rat models. Sciatic nerve laser Doppler flux in diabetic rats was variable during the 2 days following streptozotocin injection; from day 4, when the measurement was 80% of control, fluxes fell steadily and formed a… CONTINUE READING

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