Nerve growth factor suppresses prostate tumor growth.


Nerve growth factor (NGF) facilitates reinnervation of perivascular nerves that regulate vascular tone and blood flow. This study investigated whether NGF prevents tumor growth by promoting neuronal regulation of tumor blood flow. The growth rate of DU145 prostate carcinoma cells subcutaneously implanted into nude mice was significantly inhibited by… (More)


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@article{Goda2010NerveGF, title={Nerve growth factor suppresses prostate tumor growth.}, author={Mitsuhiro Goda and Saori Atagi and Keisuke Amitani and Narumi Hobara and Yoshihisa Kitamura and Hiromu Kawasaki}, journal={Journal of pharmacological sciences}, year={2010}, volume={112 4}, pages={463-6} }