Nerve growth factor sensitivity is broadly distributed among myenteric neurons of the rat colon.

@article{Lin2005NerveGF,
  title={Nerve growth factor sensitivity is broadly distributed among myenteric neurons of the rat colon.},
  author={Agueda Lin and Sandra R Lourenssen and Roger D P Stanzel and M G Blennerhassett},
  journal={The Journal of comparative neurology},
  year={2005},
  volume={490 2},
  pages={194-206}
}
Nerve growth factor (NGF) acts on the two-receptor system of trkA and p75 to mediate neuroprotection and influence phenotype and function in the peripheral nervous system, but the effects of NGF on the enteric nervous system (ENS) are virtually unknown. To establish a basis for enteric responsiveness to NGF, we studied the presence and distribution of NGF-sensitive receptors in the myenteric neurons of the normal rat colon and examined their activation via trkA phosphorylation. Fluorescent… CONTINUE READING