Nerve growth factor rapidly regulates VGF gene transcription through cycloheximide sensitive and insensitive pathways.


Nerve growth factor (NGF) initiates and maintains a regulatory cascade, involving gene induction, which results in the neuronal differentiation of PC12 cells. The VGF gene encodes one of the most rapidly induced neuronal mRNAs identified in NGF-treated PC12 cells [Science, 229 (1985) 393-395; Mol. Cell Biol., 11 (1991) 2335-2349]. In this communication we… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.