Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections.

@article{Hefti1986NerveGF,
  title={Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections.},
  author={Franz Hefti},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1986},
  volume={6 8},
  pages={
          2155-62
        }
}
Several findings obtained in recent years suggest that NGF, aside from its well-established function as a neurotrophic factor for peripheral sympathetic and sensory neurons, also has trophic influence on the cholinergic neurons of the basal forebrain. The present study assessed whether NGF was able to affect survival of central cholinergic neurons after axonal transections in adult rats. The septo-hippocampal pathway was transected unilaterally by cutting the fimbria, and animals were implanted… CONTINUE READING

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