Nerve growth factor promoter activity revealed in mice expressing enhanced green fluorescent protein.

@article{Kawaja2011NerveGF,
  title={Nerve growth factor promoter activity revealed in mice expressing enhanced green fluorescent protein.},
  author={Michael D. Kawaja and Laura J. Smithson and Janet E. Elliott and Gina Trinh and Anne-Marie Crotty and Bernadeta Michalski and Margaret Fahnestock},
  journal={The Journal of comparative neurology},
  year={2011},
  volume={519 13},
  pages={2522-45}
}
Nerve growth factor (NGF) and its precursor proNGF are perhaps the best described growth factors of the mammalian nervous system. There remains, however, a paucity of information regarding the precise cellular sites of proNGF/NGF synthesis. Here we report the generation of transgenic mice in which the NGF promoter controls the ectopic synthesis of enhanced green fluorescent protein (EGFP). These transgenic mice provide an unprecedented resolution of both neural cells (e.g., neocortical and… CONTINUE READING

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Author manuscript; available in PMC

  • J Comp Neurol
  • 2012

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