Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition.

Abstract

Male Wistar rats (3- and 20-month-old) were perfused i.c.v. with 1.5 micrograms of either nerve growth factor (NGF) or cytochrome C daily for 14 days. At the end of the infusion, the object-recognition test was carried out and extracellular acetylcholine levels (ACh) were measured in the cortex and hippocampus by transversal microdialysis technique. In 20… (More)

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Cite this paper

@article{Scali1994NerveGF, title={Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition.}, author={C. Scali and Fiorella Casamenti and Mario Pazzagli and Laura Bartolini and Giancarlo Pepeu}, journal={Neuroscience letters}, year={1994}, volume={170 1}, pages={117-20} }