Nerve growth factor concentrations in the synovial fluid from healthy dogs and dogs with secondary osteoarthritis

  title={Nerve growth factor concentrations in the synovial fluid from healthy dogs and dogs with secondary osteoarthritis},
  author={Maurizio Isola and Vanni Ferrari and Alda Miolo and Fabio Stabile and Daniele Bernardini and Paolo Carnier and Roberto Busetto},
  journal={Veterinary and Comparative Orthopaedics and Traumatology},
  pages={279 - 284}
Summary Objective: To measure the concentrations of nerve growth factor (NGF) in the synovial fluid from normal dogs and dogs with osteoarthritis (OA) secondary to common joint disorders. Methods: Nerve growth factor synovial concentrations were measured by ELISA assay in 50 dogs divided into three groups: 12 healthy, 16 affected by acute lameness within seven days before enrolment, and 22 with chronic lameness persisting by more than one month before enrolment and accompanied by radiological… 

Nerve growth factor in the equine joint.

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Nerve growth factor (NGF) autoantibodies and NGF in the synovial fluid: implications in spondylarthropathies.

A role of NGF autoantibodies and NGF in joint inflammation especially in spondylarthropathies is suggested.

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The presence of neurotrophins as well as their receptors, in particular the NGF/trkA-p75 axis in peripheral synovitis warrants further functional investigation of their active involvement in chronic inflammatory arthritis.

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