Nerve growth factor and Trk high a Y nity receptor ( TrkA ) gene expression in inflammatory bowel disease

@inproceedings{Mola2000NerveGF,
  title={Nerve growth factor and Trk high a Y nity receptor ( TrkA ) gene expression in inflammatory bowel disease},
  author={Fabio Francesco Di Mola and Helmut Friess and Zhaowen Zhu and Alexander Koliopanos and Thomas Bley and Pierluigi di Sebastiano and Paolo Innocenti and Arthur Zimmermann and W Buechler},
  year={2000}
}
Background—Nerve growth factor (NGF), a target derived factor for survival and maintenance of peripheral and central neurones, has been implicated in several chronic inflammatory processes. Aims—To analyse the concomitant presence of NGF and its high aYnity receptor TrkA in patients undergoing surgery for Crohn’s disease (CD) and ulcerative colitis (UC). Patients—CD tissues were obtained from 33 patients and UC tissue samples from 12 patients undergoing surgery. Normal intestinal tissue samples… CONTINUE READING