Nerve growth factor (NGF) has novel antidepressant-like properties in rats.

Abstract

Nerve growth factor, a neurotrophin, may have other functions, including a role in depressive disorders. The present study sought to determine whether NGF would (1) have antidepressant-like effects and (2) behave similarly to or differently from other well-recognized antidepressants. Over a broad dose-range, NGF reduced the exaggerated swim test immobility… (More)
DOI: 10.1016/j.pbb.2009.11.010

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Cite this paper

@article{Overstreet2010NerveGF, title={Nerve growth factor (NGF) has novel antidepressant-like properties in rats.}, author={David H. Overstreet and Kellie Fredericks and Darin J. Knapp and George R. Breese and John M McMichael}, journal={Pharmacology, biochemistry, and behavior}, year={2010}, volume={94 4}, pages={553-60} }