Nerve Growth Factor Signaling Regulates Motility and Docking of Axonal Mitochondria

@article{Chada2004NerveGF,
  title={Nerve Growth Factor Signaling Regulates Motility and Docking of Axonal Mitochondria},
  author={Sonita R Chada and Peter J Hollenbeck},
  journal={Current Biology},
  year={2004},
  volume={14},
  pages={1272-1276}
}
Axonal transport is thought to distribute mitochondria to regions of the neuron where their functions are required. In cultured neurons, mitochondrial transport responds to growth cone activity, and this involves both a transition between motile and stationary states of mitochondria and modulation of their anterograde transport activity. Although the exact cellular signals responsible for this regulation remain unknown, we recently showed that mitochondria accumulate in sensory neurons at… CONTINUE READING
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