Nerve Agents

  title={Nerve Agents},
  author={Jonathan Newmark},
  journal={The Neurologist},
  • Jonathan Newmark
  • Published 2007
  • The Neurologist
  • Background:Nerve agents, the deadliest of the classic chemical warfare agents, primarily function as acetylcholinesterase inhibitors and cause a rapidly progressive cholinergic crisis. Originally developed for battlefield use, they have been used in terrorist attacks and are considered threats to the civilian population. Review Summary:The pathophysiology and clinical presentation of acute nerve agent poisoning are summarized and acute treatment protocols reviewed. Timely support and antidotal… CONTINUE READING


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