Nephrotoxicity of vancomycin in patients with methicillin-resistant Staphylococcus aureus bacteraemia.

@article{Shen2011NephrotoxicityOV,
  title={Nephrotoxicity of vancomycin in patients with methicillin-resistant Staphylococcus aureus bacteraemia.},
  author={Wan-Chen Shen and Yi-Chun Chiang and Hsiang-Yin Chen and T Chen and F Yu and Chao Hsiun Tang and Yuh-Mou Sue},
  journal={Nephrology},
  year={2011},
  volume={16 8},
  pages={697-703}
}
AIM Vancomycin and teicoplanin are the two most used glycopeptides for the treatment of methicillin-resistant Staphylococcus aureus (MRSA). Vancomycin is suspected to have more nephrotoxicity but this has not been clearly established. The aim of this study was to assess its nephrotoxicity by a consensus definition of acute kidney injury (AKI): the risk (R), injury (I), failure (F), loss and end-stage renal disease (RIFLE) classification. METHODS Patients with MRSA bacteraemia who were… CONTINUE READING